Exploring the potential of targeting cytosine modifications for therapeutic interventions in genetic diseases and cancer. As our understanding of cytosine biology deepens, it will open up new avenues ...

IN the nucleic acids, cytosine is connected to a sugar residue through N 1 of the pyrimidine ring. Here we describe the results of an X-ray diffraction analysis of crystals of N 1-methyl cytosine.

Tyr 34 also accepts a hydrogen bond from the 4-amino group of one of the methylated cytosine residues, further contributing to sequence selectivity. The crucial nature of the contacts between ...

In DNA, guanine is always paired with cytosine, and the sequence of these base pairs determines the genetic code ... such as smooth muscle relaxation and visual phototransduction. In synthetic biology ...

People genetically susceptible to Huntington's disease often see their movement, mood, and cognition decline slowly over time ...

Among these mysteries are i-motifs, unusual knot-like DNA structures formed when cytosine-rich sequences fold into a four-stranded, twisted configuration. Recent research has illuminated the ...