Cell lines are used early in drug discovery and development to create relevant models that reflect human biology, in both health and disease, for in vitro research. However, engineering cell lines ...

In addition to the transiently expressed SLC protein models, there are cell line-based models of kidney transporter function such as MDCK, CHO, U2OS. Owing to the fact that they may not originate ...

The Advanced Cell Engineering and ... knock-out and knock-in cell lines using CRISPR/Cas9, providing cDNA, shRNA, and gRNA vectors individually or as custom libraries, and consultation and expert ...

In animals, effective immune responses against malignancies and against several infectious pathogens, including malaria, are mediated by T cells. Here we show that a heterologous prime-boost ...