The cell must also pass through a series of checkpoints that ensure conditions are favorable for division. In order to move from one phase of its life cycle to the next, a cell must pass through ...

CHK1 is important for the activation of S, G2 checkpoints in response to DNA damage and replicative stress and is involved ... and concept for the project that CHK1 inhibition was therapeutically ...

In addition to these decisions, which are made in the G1 phase of the cell cycle, checkpoints that operate in other phases of the cycle exert quality control by determining that certain steps have ...

A review discussing the therapeutic potentials of NK cell biology has been published in the journal Frontiers of Medicine. This exhaustion is influenced by immune checkpoint receptors, which are ...

This exhaustion is influenced by immune checkpoint receptors, which are inhibitory cell surface receptors that can suppress antitumor immunity. Notably, intracellular checkpoint molecules within ...

A review discussing the therapeutic potentials of NK cell biology has been published in the journal Frontiers of Medicine. Natural killer (NK) cells are pivotal in the innate immune response ...