Babies born with otherwise-lethal single ventricle heart defects can gain decades of life from early surgical intervention, but their lives are still fraught with medical complications that ...

This results in increased afterload on the left ventricle, an increase in systolic ... cells resulting in a decrease in intrinsic heart rate. With fibrosis of the cardiac skeleton there is ...

Over time, repetitive injury may lead to changes that resemble right (or less often) left ventricular (LV) cardiomyopathy ... a disproportionate increase in RV stroke work index relative to that of ...

this means that right ventricular (RV) function predicts survival. Our group is interested in understanding how the right heart fails and identifying therapeutic targets for the RV- a disease in which ...

The electrical impulse then reaches the left ventricle from the right ventricle ... while the other half are idiopathic or due to fibrosis of the cardiac conduction system which occurs during ...

The left and right ventricles each pump the same volume of blood through the aorta and pulmonary artery. The volume of blood pumped through each ventricle per minute can be calculated as cardiac ...

and calcium channel blockers are used in selected patients to decrease left ventricular hypertrophy. To decrease myocardial fibrosis, aldosterone antagonists have a potential therapeutic role.

The left ventricle is the heart’s main pumping chamber ... testing a drug to repair lungs damaged by idiopathic pulmonary ...

This impairment in septal E CC outperformed left ventricular ejection fraction (LVEF), a conventional measure of heart function, in distinguishing patients with DMD from those without. When ...

Dr. Thomas's research interests relate to cardiac structure and function. More specifically he has been interested in adaptations made by the heart to both physiological and pathological overload.