Using CRISPR technology that targets RNA instead of DNA, researchers at New York University and the New York Genome Center ...

A fresh wave of gene-editing therapies is surging to the fore — even as the field wrestles with the challenge of getting the first generation of expensive and complex CRISPR treatments to the ...

Researchers have uncovered a serious side effect of using the CRISPR-Cas gene scissors. A molecule designed to make the process more efficient destroys parts of the genome. Genome editing with ...

图2. 比较knockin实验中导入dsDNA和ssDNA所产生的细胞毒性（细胞系为Cellartis hiPSC18） ssDNA作为CRISPR基因敲入供体模板，由于其非特异性整合概率低、细胞毒性低的特性可以轻松实现准确CRISPR基因敲入 ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

实现更特异、更高效的基因敲入（knockin）！ CRISPR/Cas9和其它基因编辑工具已经被成功应用于获得基因敲除突变（knockout），但众多事实证明在基因敲入上的应用有很大的难度。基因敲入所面临的 ...

CRISPR Therapeutics' Q3 saw reduced expenses and slow Casgevy launch, resulting in a revenue miss but a narrowed net loss. Financial health remains strong with a cash runway of approximately 5 ...