RLF-B/Cdt1 and Mcm2-7 are involved in recruiting both Xic1 (through Cdc6 and cyclin E/Cdk2) and SCF (through Mcm2–7), this provides a mechanism for bringing together SCF and its substrate at ...

Cyclin-dependent kinases (CDKs) trigger the transition from G1 to S phase and from G2 to M phase by phosphorylating distinct sets of substrates. (B) CDK1 and CDK2 bind to multiple cyclins (cyclin ...