近日，美国圣路易斯华盛顿大学医学院团队开发了一种基于 T 细胞受体的自身免疫性 CD4+T 细胞疗法，可用于治疗脊髓损伤，并通过 mRNA 介导的短暂 T 细胞受体（TCR，T cell receptor）表达来最小化潜在的副作用。

The following is a summary of “Similar humoral responses but distinct CD4+ T cell transcriptomic profiles in older adults ...

Researchers have discovered that methotrexate (MTX) therapy may substantially diminish vaccine-induced CD4 T cell activation ...

By Pooja Toshniwal Paharia Study reveals that moderate fever temperatures (39°C) improve metabolism, proliferation, and ...

引言肿瘤免疫微环境对癌症的发生、预后及治疗的贡献已广为认可，尤其是在固有免疫因素和T细胞亚群的研究方面。然而，尽管有证据表明肿瘤浸润B细胞在多种癌症中占据显著比例，甚至在某些情况下占所有肿瘤浸润淋巴细胞的40%，但肿瘤免疫微环境中B细胞的研究相对较少 ...

Immatics, a biotech company working on promising cell-based immunotherapies for solid cancers, has a promising TCR-engineered ...

This valuable study reports on a novel role of PD-1 in early T cell differentiation, showing that PD-1 stimulation impairs Th2 differentiation more effectively than that of Th1, with implications for ...

New non-human primate data show highly selective in vivo delivery of mRNA to T cells with a cell-targeted lipid nanoparticle ...

CAR-T cell products’ quality control standards incorporate characterization, uniformity, and purity testing to ensure and ...

Using Mendelian randomization analysis, researchers found evidence that 2 small groups of immunophenotypes are linked to either greater or lesser odds of developing pulmonary arterial hypertension ...

MANILA, Oct. 11 (Xinhua) -- The Philippines' Department of Health (DOH) on Friday expressed concern over the rising number of newly diagnosed advanced HIV disease (AHD) in the country. The latest data ...

The firm is gearing up for a registration-directed trial based on a positive Phase Ib readout and after discussions with US ...