Researchers have discovered that methotrexate (MTX) therapy may substantially diminish vaccine-induced CD4 T cell activation ...

A new study identifies potential immune profile differences in patients with chronic lymphocytic leukemia (CLL) that may lead ...

近日，美国圣路易斯华盛顿大学医学院团队开发了一种基于 T 细胞受体的自身免疫性 CD4+T 细胞疗法，可用于治疗脊髓损伤，并通过 mRNA 介导的短暂 T 细胞受体（TCR，T cell receptor）表达来最小化潜在的副作用。

The following is a summary of “Similar humoral responses but distinct CD4+ T cell transcriptomic profiles in older adults ...

This valuable study reports on a novel role of PD-1 in early T cell differentiation, showing that PD-1 stimulation impairs Th2 differentiation more effectively than that of Th1, with implications for ...

By Pooja Toshniwal Paharia Study reveals that moderate fever temperatures (39°C) improve metabolism, proliferation, and ...

CD4-cell counts and T-cell activation levels were determined in four groups of patients: 30 HIV-infected elite controllers, 47 HIV-uninfected persons, 187 treated HIV-infected persons with ...

A second CAR T-cell expansion started day on 39 but consisted of multiple CAR+ populations. Two CAR+ populations were characterized by CD4+ or CD8+ expression, and one population was negative for ...

This important study provides solid in-vivo evidence that CCR4 regulates the early inflammatory response during atherosclerotic plaque formation. The authors propose that altered T-cell response plays ...

“While the effects of LANCL2 on CD4+ T cell differentiation and function have been characterized in other autoimmune diseases such as IBD, this paper describes for the first time an additional ...