Relatively unknown brain cells—"astrocytes"—are believed to play an important role. At the Uppsala Biomedical Center, lab researchers are attempting to learn more about their function in order ...

The potential effects of astrocyte dysfunction in neurodegenerative ... been hypothesized to result from the failure of astrocytic functions that require cell–cell coupling to maintain their ...

allowing astrocytes to sense and regulate multiple aspects of brain function. Unlike neurons, astrocytes are not electrically active (i.e., their activation does not lead to the generation of action ...

Spinal cord injuries (SCI) are challenging to treat due to the limited regenerative capacity of the central nervous system.

Dr. Liddelow explains how he and his team approached their research, including the initial questions they set out to answer, the roadblocks they encountered, and how they discovered a neurotoxic form ...

Our lab is interested in the cellular and molecular mechanisms that define and regulate the diversity of astrocyte function in the intact and injured or diseased CNS. We use mouse genetics to ...

It discusses their role in the remodelling of the structure of the lamina cribrosa and the effect that this might have on axon function. Recent evidence has shown that the modulation of astrocyte ...