Age-associated physiological and pharmacokinetic changes increase anticholinergic drug effects in later life. Those with cognitive impairment and neurodegeneration are particularly susceptible to ...

Although bronchial hyperresponsiveness to cholinergic agents is a main feature of asthma, the role of anticholinergic drugs in chronic asthma management has been largely underestimated.

Like Benadryl, these antidepressants exhibit anticholinergic effects, but there’s inconsistent scientific evidence that they increase the risk of dementia. “If you’re taking these ...

The findings were alarming. People who took at least one anticholinergic drug had a 47% higher risk of developing memory ...

Concomitant other diphenhydramine- or doxylamine-containing products (including topicals): not recommended. Additive effects with other anticholinergics, antihistamines, sedatives, tranquilizers.

Nursing mothers. Alcohol, other CNS depressants potentiate CNS depression. Additive anticholinergic effects with other anticholinergics, antihistamines (eg, meclizine), tricyclic antidepressants ...

so combining it with another medicine with an anticholinergic effect can result in increased or more severe side effects. Healthcare providers will avoid the combination when possible. However ...