Age-associated physiological and pharmacokinetic changes increase anticholinergic drug effects in later life. Those with cognitive impairment and neurodegeneration are particularly susceptible to ...

Consider the following: Many other medications may have mild to moderate anticholinergic effects. These effects can add up if ...

In addition, anticholinergics may antagonize the effects of drugs such as donepezil, which are thought to improve cognition by enhancing cholinergic function in patients with Alzheimer's disease (AD).

The findings were alarming. People who took at least one anticholinergic drug had a 47% higher risk of developing memory ...

Chlorpromazine HCl 25mg/mL; for IV inj after dilution or IM inj; contains sulfites; multidose vials contain benzyl alcohol. <6months: not recommended. ≥6months: 0.25mg/lb IM every 6–8hrs if ...

Nursing mothers. Alcohol, other CNS depressants potentiate CNS depression. Additive anticholinergic effects with other anticholinergics, antihistamines (eg, meclizine), tricyclic antidepressants ...