De Duve named these new organelles "lysosomes" to reflect their lytic nature. That same year, Alex Novikoff from the University of Vermont visited de Duve´s laboratory. An experienced ...

But why do certain variants of this lipid transporter protect the brain, while others endanger it? A suite of experiments published in the November 7 Cell suggests that the answer lies in lysosomes.

The biotech is focusing on precision, small-molecule medicines that work via a process known as cellular clearance by activating the lysosome, sometimes referred to as the cell’s recycling and ...

To break down and recycle these nutrients, the cells rely on tiny organelles called lysosomes. When functional, a lysosome ...

While all three genotypes of mice performed similarly to wild-type animals on multiple behavioral and spatial memory tests, they faltered in tests of working memory. APP-KI had a subtle deficit, which ...